Fei Wang





  • 2013-2018 中国科学院大学上海应用物理研究所,无机化学,博士

  • 2009-2013 中国科学技术大学,应用物理学,学士


  • 2021.1~ : 上海交通大学变革性分子前沿科学中心,长聘教轨副教授

  • 2018-2020 上海交通大学化学化工学院,博士后


  • DNA存储

  • DNA计算

  • 单分子成像


  • 国家自然科学基金青年项目,21904060,基于矩形DNA折纸的纳米成像于调控平台用于单分子转录行为研究,2020.01-2022.12,主持



  • Hao, Y.; Li, M.; Zhang, Q.; Shi, J.; Li, J.; Li, Q.*; Fan, C.*; Wang, F.* DNA Origami-Based Single-Molecule CRISPR Machines for Spatially Resolved Searching. Angew. Chem., Int. Ed. 2022. 61, e202205460

  • Xie, N.; Li, M.; Wang, Y.; Lv, H.; Shi, J.; Li, J.; Li, Q.; Wang, F.*; Fan, C. Scaling Up Multi-Bit DNA Full Adder Circuits with Minimal Strand Displacement Reactions. J. Am. Chem. Soc. 2022, 144 (21), 9479–9488.

  • Jiao, K.; Yan, Q.; Guo, L.; Qu, Z.; Cao, S.; Chen, X.; Li, Q.; Zhu, Y.; Li, J.; Wang, L.; Fan, C.; Wang, F.* Poly-Adenine-Based Spherical Nucleic Acids for Efficient Live-Cell MicroRNA Capture. Angew. Chem., Int. Ed. 2021, 60 (26), 14438–14445

  • Hao, Y.; Li, Q.; Fan, C.*; Wang, F.* Data Storage Based on DNA. Small Struct. 2021, 2 (2), 2000046.

  • Wang, F.; Hao, Y.; Li, Q.; Li, J.; Zhang, H.; Zhang, X.; Wang, L.; Bustamante, C.*; Fan, C.* Programming PAM Antennae for Effcient CRISPR-Cas9 DNA Editing. Sci. Adv. 2020, 6 (19), eaay9948.

  • Lv, H.; Li, Q.; Shi, J.; Fan, C.*; Wang, F.*. Biocomputing Based on DNA Strand Displacement Reactions. ChemPhysChem 2021, 22 (12), 1151–1166.


  • Wang, F.#; Lv, H.#; Li, Q.; Li, J.; Zhang, X.; Shi, J.; Wang, L.; Fan, C. Implementing Digital Computing with DNA-Based Switching Circuits. Nat. Commun. 2020, 11 (1), 121. (# Co-first author)

  • Hao, Y.; Li, J.; Li, Q.; Zhang, L.; Shi, J.; Zhang, X.; Aldalbahi, A.; Wang, L.; Fan, C.*; Wang, F.* Programmable Live-Cell CRISPR Imaging with Toehold-Switch-Mediated Strand Displacement. Angew. Chem., Int. Ed. 2020, 59 (46), 20612–20618.

  • Yao, G.#; Zhang, F.#; Wang, F.#; Peng, T.; Liu, H.; Poppleton, E.; Šulc, P.; Jiang, S.; Liu, L.; Gong, C.; Jing, X.; Liu, X.; Wang, L.; Liu, Y.; Fan, C.; Yan, H. Meta-DNA Structures. Nat. Chem. 2020, 12 (11), 1067–1075. (# Co-first author)

  • Chao, J.#; Wang, J.#; Wang, F.#; Ouyang, X.#; Kopperger, E.; Liu, H.; Li, Q.; Shi, J.; Wang, L.; Hu, J.; Wang, L.; Huang, W.; Simmel, F. C.; Fan, C. Solving Mazes with Single-Molecule DNA Navigators. Nat. Mater. 2019, 18 (3), 273–279. # Co-first author

  • Wang, F.; Fan, C.* DNA REACTION NETWORKS Providing a Panoramic View. Nat. Chem.2016, 8 (8), 738–740.

  • Wang, F.; Zhang, X.; Liu, X.; Fan, C.; Li, Q.* Programming Motions of DNA Origami Nanomachines. Small 2019, 15 (26).

  • Zhang, L.#; Wang, F.#; Li, Q.; Wang, L.; Fan, C.; Li, J.; Zhu, Y. Classifying Cell Types with DNA-Encoded Ligand–Receptor Interactions on the Cell Membrane. Nano Lett. 2020, 20 (5), 3521–3527. (# Co-first author)

  • Zhang, Y.#; Wang, F.#; Chao, J.; Xie, M.; Liu, H.*; Pan, M.; Kopperger, E.; Liu, X.; Li, Q.; Shi, J.; Wang, L.; Hu, J.; Wang, L.; Simmel, F. C.; Fan, C.* DNA Origami Cryptography for Secure Communication. Nat. Commun. 2019, 10 (1), 5469. (# Co-first author)

  • Zhang, P.#; Wang, F.#; Liu, W.; Mao, X.; Hao, C.; Zhang, Y.*; Fan, C.; Hu, J.; Wang, L.*; Li, B.* Quantitative Measurement of Spatial Effects of DNA Origami on Molecular Binding Reactions Detected Using Atomic Force Microscopy. ACS Appl. Mater. Interfaces 2019, 11 (24), 21973–21981. (# Co-first author)